Spatial heterogeneity and evolutionary dynamics modulate time to recurrence in continuous and adaptive cancer therapies
J. Gallaher, P. M. Enriquez-Navas, K. A. Luddy, R. A. Gatenby, and A. R. A. Anderson
Comparing continuous treatment (CT), adaptive therapy emphasizing dose modulation (AT1), & adaptive therapy emphasizing treatment vacations (AT2)
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Fig3A/4A: Sensitive Homogeneous
Fig3B: Sensitive Heterogeneous
Fig3C: Resistant Homogeneous
Fig3D: Resistant Heterogeneous
Fig5A: Sensitive Heterogeneous Invasive
Fig6A: Sensitive Heterogeneous Drift
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